Michael Brudno

MOHCCN Steering CommitteeResearcher

Working Groups

Michael Brudno is a Professor in the Department of Computer Science at the University of Toronto, as well as the Chief Data Scientist at the University Health Network (UHN). He is also a faculty member at the Vector Institute for Artificial Intelligence and the Scientific Director of HPC4Health, a private computing cloud for Ontario hospitals. His main research interest is the development of computational methods for the analysis of clinical and genomic datasets, especially the capture of precise clinical data from clinicians using effective user interfaces, and its utilization in the automated analysis of genomes. This work focuses on the capture of structured phenotypic data from clinical encounters, using both refined User Interfaces, and mining of unstructured data (based on Machine Learning methodology), and the analysis of omics data (genome, transcriptome, epigenome) in the context of the structured patient phenotypes, mostly for rare diseases. His overall research goal is to enable the seamless automated analysis of patient omics data based on automatically captured information from a clinical encounter, thus streamlining clinical workflows and enabling faster and better treatments.

After receiving a BA in Computer Science and History from UC Berkeley, Michael received his PhD from the Computer Science Department of Stanford University, working on algorithms for whole genome alignments. He completed a postdoctoral fellowship at UC Berkeley and was a Visiting Scientist at MIT. He is the recipient of the Ontario Early Researcher Award and the Sloan Fellowship, as well as the Outstanding Young Canadian Computer Scientist Award.